Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | KLK8 | O60259 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KLK2 | P20151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815209 | 0.82 | ELANE (0.38) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL11390682 | 0.81 | ELANE (0.50) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL10458711 | 0.79 | ANPEP (0.41) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL11388122 | 0.76 | MEN1 (0.43) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL11388332 | 0.74 | CYP3A4 (0.46) | TP53ALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL11795459 | 0.73 | ELANE (0.47) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL11398405 | 0.69 | ATM (0.41) | ELANETP53MEN1KMT2AALDH1A1 | |
| SCHEMBL6996344 | 0.68 | CHRM1 (0.51) | TP53KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10458760 | 0.65 | GAA (0.48) | ELANETP53KLK1ALDH1A1GAA | |
| SCHEMBL17378451 | 0.65 | BTN3A1 (0.45) | ELANEMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258040-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4060687-A | Cephalosporins having a 3-α substituted alkyl grouping | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-3947413-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-03-30 | — | — | US | disclosed |