Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383381 | 0.92 | ELANE (0.38) | CYP3A4PTGS1USP2CHRM1ALDH1A1 | |
| SCHEMBL11078285 | 0.84 | CYP3A4 (0.45) | CYP3A4PTGS1USP2CHRM1ALDH1A1 | |
| SCHEMBL11386850 | 0.83 | CTDSP1 (0.40) | ALDH1A1L3MBTL1CYP2C19MAPK1LMNA | |
| SCHEMBL11381175 | 0.81 | MAPT (0.42) | CYP3A4PTGS1USP2CHRM1ALDH1A1 | |
| SCHEMBL11079376 | 0.76 | ALDH1A1 (0.44) | CYP3A4PTGS1ALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL11084708 | 0.76 | ALDH1A1 (0.53) | CYP3A4PTGS1USP2CHRM1ALDH1A1 | |
| SCHEMBL11084713 | 0.76 | ALDH1A1 (0.53) | CYP3A4PTGS1USP2CHRM1ALDH1A1 | |
| SCHEMBL11077988 | 0.76 | PTGS1 (0.37) | CYP3A4PTGS1USP2CHRM1 | |
| SCHEMBL11077991 | 0.76 | PTGS1 (0.37) | CYP3A4PTGS1USP2CHRM1 | |
| SCHEMBL11078754 | 0.75 | PTGS1 (0.44) | CYP3A4PTGS1USP2CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |