Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.39 |
| ▸ | CTSS | P25774 | 18/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139300 | 1.00 | CTSL (0.39) | CTSLCTSSCTSB | |
| SCHEMBL1139212 | 0.94 | CTSS (0.39) | CTSLCTSSCTSB | |
| SCHEMBL1139726 | 0.94 | CTSS (0.39) | CTSLCTSSCTSB | |
| SCHEMBL1139768 | 0.91 | GRM2 (0.40) | CTSLCTSSCTSB | |
| SCHEMBL1139658 | 0.91 | GRM2 (0.40) | CTSLCTSSCTSB | |
| SCHEMBL1139986 | 0.88 | GRM2 (0.36) | CTSLCTSSCTSB | |
| SCHEMBL1139553 | 0.88 | GRM2 (0.36) | CTSLCTSSCTSB | |
| SCHEMBL1139215 | 0.85 | GRM2 (0.34) | CTSLCTSS | |
| SCHEMBL1139350 | 0.85 | GRM2 (0.34) | CTSLCTSS | |
| SCHEMBL1139795 | 0.85 | CTSL (0.38) | CTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893099-B2 | Cyclopentane derivatives | HOFFMAN-LA ROCHE INC. (US) | 2011-02-22 | — | — | US | claimed |
| US-7893099-B2 | Cyclopentane derivatives | HOFFMAN-LA ROCHE INC. (US) | 2011-02-22 | — | — | US | disclosed |