Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.63 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206365 | 0.92 | ACHE (0.60) | ACHEEPHX1 | |
| SCHEMBL10813916 | 0.84 | ACHE (0.71) | ACHEEPHX1NAAANPC1RAB9A | |
| SCHEMBL28075463 | 0.84 | ACHE (0.71) | ACHEEPHX1NAAANPC1RAB9A | |
| SCHEMBL11493296 | 0.84 | ACHE (0.71) | ACHEEPHX1NAAANPC1RAB9A | |
| SCHEMBL5545156 | 0.84 | ACHE (0.71) | ACHEEPHX1NAAANPC1RAB9A | |
| SCHEMBL22556158 | 0.84 | — | — | |
| SCHEMBL7155278 | 0.82 | ACHE (0.89) | ACHEEPHX1EPHX2 | |
| SCHEMBL5830700 | 0.82 | ACHE (0.89) | ACHEEPHX1EPHX2 | |
| SCHEMBL13700183 | 0.82 | ACHE (0.89) | ACHEEPHX1EPHX2 | |
| SCHEMBL1026398 | 0.82 | ACHE (0.89) | ACHEEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276285-A | SYNERGISTIC BACTERICIDES | PFIZER INC. (US) | 1981-06-30 | — | — | US | disclosed |
| US-4234579-A | Penicillanic acid 1,1-dioxides as β-lactamase inhibitors | PFIZER INC. (US) | 1980-11-18 | — | — | US | disclosed |