Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BTK | Q06187 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | PKM | P14618 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171430 | 0.76 | MEN1 (0.69) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL15886674 | 0.75 | MEN1 (0.51) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL230069 | 0.75 | NPC1 (0.56) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL15886668 | 0.74 | MEN1 (0.50) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL8927008 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL20982597 | 0.71 | ALDH1A1 (0.83) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL6016075 | 0.70 | MEN1 (0.49) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL3476023 | 0.70 | GSR (0.65) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL21318393 | 0.70 | PDGFRB (0.52) | KDM4EALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL517706 | 0.70 | MEN1 (0.77) | KDM4EALDH1A1MAPTTHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269846-A | BENZOHETEROCYCLIC OXADIAZOLONES AND TRIAZOLONES | USV PHARMACEUTICAL CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |