Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22130216 | 0.82 | BRD4 (0.48) | BRD4MAPTMEN1KMT2ANPC1 | |
| SCHEMBL11254410 | 0.80 | BRD4 (0.49) | BRD4MAPTKDM4CKDM5B | |
| SCHEMBL1375300 | 0.79 | NPC1 (0.48) | BRD4MAPTKDM4CMEN1KMT2A | |
| SCHEMBL22130283 | 0.79 | BRD4 (0.48) | BRD4MAPT | |
| SCHEMBL11391433 | 0.78 | HRH3 (0.52) | MEN1KMT2ASCN4A | |
| SCHEMBL16202036 | 0.78 | ALDH1A1 (0.52) | RAD51MAPTMEN1KMT2ANPC1 | |
| SCHEMBL22130176 | 0.76 | BRD4 (0.46) | BRD4MAPTKMT2A | |
| SCHEMBL11395461 | 0.75 | SMN1; SMN2 (0.43) | BRD4MAPTKMT2ANPC1RAB9A | |
| SCHEMBL11394742 | 0.74 | BRD4 (0.44) | BRD4RAD51MAPTKDM4CNPC1 | |
| SCHEMBL10112053 | 0.74 | SMN1; SMN2 (0.59) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289774-A | Lipid lowering and anti-thrombotic 6-arylpyridazin-3-ones and a process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-15 | — | — | US | disclosed |