Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378914 | 0.84 | DNMT3B (0.47) | DNMT3BKMT2ACYP3A4MAOBKDM4E | |
| SCHEMBL11384224 | 0.80 | KMT2A (0.38) | KMT2AMEN1TSHRMAPT | |
| SCHEMBL11389301 | 0.77 | ALDH1A1 (0.36) | KMT2AMEN1CYP3A4ALOX15TSHR | |
| SCHEMBL11386038 | 0.77 | DNMT3B (0.47) | DNMT3BKMT2AMEN1MAOBKDM4E | |
| SCHEMBL11391280 | 0.75 | DNMT3B (0.48) | DNMT3BKMT2AMEN1CYP3A4MAOB | |
| SCHEMBL25201529 | 0.71 | DNMT3B (0.52) | DNMT3BKMT2ACYP3A4MAOBKDM4E | |
| SCHEMBL9056733 | 0.71 | DNMT3B (0.56) | DNMT3BMAOBKDM4EADORA3AR | |
| SCHEMBL9056735 | 0.71 | DNMT3B (0.56) | DNMT3BMAOBKDM4EADORA3AR | |
| SCHEMBL11393327 | 0.71 | RET (0.41) | KMT2AMEN1CYP3A4ALOX15TSHR | |
| SCHEMBL5313705 | 0.70 | DNMT3B (0.57) | DNMT3BCYP3A4TSHRMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261988-A | ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-14 | — | — | US | disclosed |