Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 6/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396876 | 0.89 | MAPT (0.51) | DNMT3BNFKB1NFKB2RELAADORA3 | |
| SCHEMBL25201529 | 0.78 | DNMT3B (0.52) | DNMT3BNFKB1NFKB2RELAADORA3 | |
| Flavanone SCHEMBL5796766 | 0.78 | AR (0.68) | ADORA3MAOBKDM4ECYP19A1AR | |
| SCHEMBL30300555 | 0.75 | MAOB (0.50) | DNMT3BADORA3MAOBKDM4ECYP19A1 | |
| SCHEMBL9056733 | 0.75 | DNMT3B (0.56) | DNMT3BNFKB1NFKB2RELAADORA3 | |
| SCHEMBL29356678 | 0.75 | MAOB (0.50) | DNMT3BADORA3MAOBKDM4ECYP19A1 | |
| SCHEMBL9056735 | 0.75 | DNMT3B (0.56) | DNMT3BNFKB1NFKB2RELAADORA3 | |
| SCHEMBL2009148 | 0.75 | MAOB (0.50) | DNMT3BADORA3MAOBKDM4ECYP19A1 | |
| SCHEMBL2009150 | 0.75 | MAOB (0.50) | DNMT3BADORA3MAOBKDM4ECYP19A1 | |
| SCHEMBL7190338 | 0.74 | SIRT1 (0.42) | DNMT3BMAOBKDM4ECYP19A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665467-A2 | FLAVONOL COMPOSITIONS | Ono, Mitsunori (US) | 2013-11-27 | — | — | EP | disclosed |
| WO-2012099930-A3 | FLAVONOL COMPOSITIONS | ONO MITSUNORI (US) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012099930-A2 | FLAVONOL COMPOSITIONS | ONO MITSUNORI (US) | 2012-07-26 | — | — | WO | disclosed |
| US-20120183587-A1 | FLAVONOL COMPOSITIONS | LINES, THOMAS CHRISTIAN (CH) | 2012-07-19 | — | — | US | disclosed |
| EP-1856085-A1 | FLAVONOID COMPOUNDS AND USES THEREOF | Howard Florey Institute of Experimental Physiology and Medicine (AU) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006094357-A1 | FLAVONOID COMPOUNDS AND USES THEREOF | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120183587-A1 | FLAVONOL COMPOSITIONS | CYP2F1, F3, TEAD3 | DNMT3B 292/4885NFKB1 1515/4885NFKB2 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.