Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670768 | 0.90 | PLEC (0.53) | TP53POLBTHRBBLMTDP1 | |
| SCHEMBL11387022 | 0.90 | TP53 (0.43) | TP53POLBTHRBBLMTDP1 | |
| SCHEMBL13807802 | 0.77 | TP53 (0.53) | TP53POLBMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL13808127 | 0.75 | TP53 (0.64) | TP53KDM4ESMN1; SMN2PLECNPSR1 | |
| SCHEMBL9511152 | 0.75 | KDM4E (0.52) | TP53POLBTHRBBLMTDP1 | |
| SCHEMBL4668620 | 0.75 | TP53 (0.60) | TP53POLBMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4668629 | 0.74 | PLEC (0.49) | TP53POLBMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL13808239 | 0.74 | TP53 (0.73) | TP53MAPTKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL4669703 | 0.74 | PLEC (0.54) | TP53POLBKDM4ESMN1; SMN2PLEC | |
| SCHEMBL15485372 | 0.74 | RARA (0.41) | TP53PLECLMNACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263207-A | ANTIALLERGENS | MERCK & CO., INC. (US) | 1981-04-21 | — | — | US | disclosed |