Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | OGT | O15294 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18703572 | 0.70 | — | — | |
| SCHEMBL171230 | 0.69 | CRBN (0.40) | MAPTRECQLBLMCRBNTRIM24 | |
| SCHEMBL2762093 | 0.67 | ALDH1A1 (0.42) | MAPTRECQLBLMCRBNTRIM24 | |
| SCHEMBL502060 | 0.67 | ALDH1A1 (0.42) | MAPTRECQLBLMCRBNTRIM24 | |
| SCHEMBL9533020 | 0.65 | — | — | |
| SCHEMBL10638515 | 0.65 | TRIM24 (0.47) | CRBNTRIM24TRIM33 | |
| SCHEMBL13665462 | 0.64 | CRBN (0.47) | MAPTRECQLBLMCRBNTRIM24 | |
| Methyl Alcohol SCHEMBL9275780 | 0.63 | CRBN (0.35) | MAPTRECQLBLMCRBNTRIM24 | |
| SCHEMBL18642871 | 0.62 | TRIM24 (0.50) | CRBNTRIM24TRIM33 | |
| SCHEMBL5132370 | 0.62 | HPGD (0.36) | MAPTRECQLBLMHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256639-A | Process for the synthesis of isatin derivatives | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO (IT) | 1981-03-17 | — | — | US | disclosed |