Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29697065 | 0.76 | CRBN (0.38) | HPGDHTTMEN1ALDH1A1MAPT | |
| SCHEMBL13989473 | 0.67 | — | — | |
| SCHEMBL1763886 | 0.67 | CRBN (0.48) | HPGDHTTMEN1ALDH1A1MAPT | |
| SCHEMBL9731787 | 0.65 | CRBN (0.46) | HPGDHTTMEN1ALDH1A1MAPT | |
| SCHEMBL6828934 | 0.65 | GSK3A (0.34) | HPGDHTTMEN1ALDH1A1MAPT | |
| SCHEMBL11397272 | 0.62 | KDM4E (0.33) | HPGDHTTMAPTBLMRECQL | |
| SCHEMBL9359596 | 0.62 | CRBN (0.50) | HPGDHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL41851 | 0.61 | — | — | |
| SCHEMBL8014236 | 0.59 | MAPT (0.41) | HPGDHTTMEN1ALDH1A1MAPT | |
| SCHEMBL13752617 | 0.59 | CRBN (0.60) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183002-B2 | Autoantibody enhanced immunoassays and kits | ABBOTT LABORATORIES (US) | 2012-05-22 | — | — | US | disclosed |