SCHEMBL11397286

SCHEMBL11397286

O=C(O)Nc1ccc(Oc2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.57
FNTB P49356 2/20 0.57
KMO O15229 1/20 0.54
HSP90AA1 P07900 1/20 0.50
MEN1 O00255 2/20 0.49
LMNA P02545 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
EPHX1 P07099 2/20 0.49
EPHX2 P34913 2/20 0.49
STK39 Q9UEW8 1/20 0.48
PGR P06401 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
RNF4 P78317 1/20 0.47
NPC1 O15118 1/20 0.47
ADORA3 P0DMS8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9813659 0.84 ALDH1A1 (0.60) MEN1LMNAKMT2AMAPTNPSR1
SCHEMBL11390139 0.82 ALDH1A1 (0.58) FNTAFNTBLMNAKMT2AMAPT
SCHEMBL11644067 0.81 FNTA (0.59) FNTAFNTBKMT2ACA12CA1
SCHEMBL1092135 0.80 EPHX1 (0.73) MEN1LMNAKMT2AMAPTEPHX1
SCHEMBL11643151 0.79 XIAP (0.66) FNTAFNTBMEN1LMNAKMT2A
SCHEMBL4653369 0.78 HPGD (0.70) LMNAEPHX1PGRCA12CA1
Hydrochloric Acid SCHEMBL11153269 0.78 EPHX1 (0.70) MEN1LMNAKMT2AMAPTEPHX1
Fluoride SCHEMBL11787935 0.78 EPHX1 (0.70) MEN1LMNAKMT2AMAPTEPHX1
SCHEMBL11008724 0.78 EPHX1 (0.81) MEN1LMNAKMT2AMAPTNPSR1
SCHEMBL2716095 0.77 KMO (0.73) KMOHSP90AA1EPHX2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4279637-A Herbicidal N-substituted 4-imidazolin-2-ones VELSICOL CHEMICAL CORPORATION (US) 1981-07-21 US disclosed