Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.73 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875555 | 0.83 | RAB9A (0.55) | DAOLTB4RTP53RAB9APTGER1 | |
| SCHEMBL11402067 | 0.82 | DAO (0.51) | DAOLTB4RTP53RAB9APTGER1 | |
| SCHEMBL7829717 | 0.81 | ERCC5 (0.53) | DAOLTB4RTP53RAB9APTGER1 | |
| SCHEMBL11397918 | 0.80 | SMN1; SMN2 (0.50) | DAOLTB4RTP53RAB9ALMNA | |
| SCHEMBL4670642 | 0.80 | DAO (0.49) | DAOLTB4RTP53RAB9APTGER1 | |
| SCHEMBL4670645 | 0.80 | DAO (0.49) | DAOLTB4RTP53RAB9APTGER1 | |
| SCHEMBL4171556 | 0.75 | DAO (0.68) | DAOTP53RAB9ALMNAGAA | |
| SCHEMBL11400603 | 0.75 | DAO (0.58) | DAOTP53RAB9ALMNAMEN1 | |
| SCHEMBL13084323 | 0.75 | DAO (0.58) | DAOTP53RAB9ALMNAGAA | |
| SCHEMBL5114483 | 0.74 | LTB4R (0.56) | DAOLTB4RRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101098852-A | Glycogen phosphorylase inhibitor compounds and pharmaceutical compositions thereof | SMITHKLINE BEECHAM CORP (US) | 2008-01-02 | — | — | CN | disclosed |
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |