Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | VEGFA | P15692 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958979 | 0.84 | KCNK3 (0.34) | KCNK3KCNK9RXFP1IRAK4CA1 | |
| SCHEMBL1465246 | 0.77 | IRAK4 (0.47) | IRAK4CA1CA2CA7CA9 | |
| SCHEMBL16953645 | 0.76 | KCNK3 (0.37) | KCNK3KCNK9RXFP1IRAK4CA1 | |
| SCHEMBL28310921 | 0.75 | GABRA1 (0.38) | KCNK3KCNK9RXFP1IRAK4CA1 | |
| SCHEMBL2814633 | 0.75 | IRAK4 (0.44) | KCNK3KCNK9IRAK4CA1CA2 | |
| SCHEMBL16953643 | 0.75 | KCNK3 (0.36) | KCNK3KCNK9RXFP1IRAK4CA1 | |
| SCHEMBL11397648 | 0.74 | ERN1 (0.40) | KCNK3KCNK9RXFP1IRAK4CA1 | |
| SCHEMBL16959516 | 0.74 | CA1 (0.38) | KCNK3KCNK9RXFP1IRAK4CA1 | |
| SCHEMBL10617132 | 0.73 | IRAK4 (0.49) | KCNK3KCNK9RXFP1IRAK4ALDH1A1 | |
| SCHEMBL2186181 | 0.71 | KCNK3 (0.34) | KCNK3KCNK9RXFP1IRAK4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283344-A | Process for producing 1,1,3,3-tetrafluoro-1,3-dihydro-isobenzofuran | NIHON NOHYAKU CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |