Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | PTGIR | P43119 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388020 | 1.00 | PTGS1 (0.41) | PTGS1PTGS2PTGIRLMNATSHR | |
| SCHEMBL11401238 | 1.00 | PTGS1 (0.41) | PTGS1PTGS2PTGIRLMNATSHR | |
| SCHEMBL11388439 | 1.00 | PTGS1 (0.41) | PTGS1PTGS2PTGIRLMNATSHR | |
| SCHEMBL828869 | 0.93 | KDM4E (0.42) | LMNATSHRKDM4E | |
| SCHEMBL11396114 | 0.87 | CYP1A2 (0.34) | TSHR | |
| SCHEMBL11400675 | 0.87 | CYP1A2 (0.34) | TSHR | |
| SCHEMBL11388926 | 0.79 | CYP1A2 (0.36) | LMNATSHR | |
| Tetrazole SCHEMBL9733152 | 0.79 | KDM4E (0.36) | TSHRKDM4E | |
| SCHEMBL10974169 | 0.78 | MAPK1 (0.46) | PTGS1PTGS2PTGIRLMNATSHR | |
| SCHEMBL11356709 | 0.77 | CA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4286089-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| US-4220644-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |