Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388020 | 0.93 | PTGS1 (0.41) | KDM4ETSHRLMNA | |
| SCHEMBL11397997 | 0.93 | PTGS1 (0.41) | KDM4ETSHRLMNA | |
| SCHEMBL11388439 | 0.93 | PTGS1 (0.41) | KDM4ETSHRLMNA | |
| SCHEMBL829121 | 0.89 | EGLN3 (0.44) | ALDH1A1KMOCYP1A2MAPK1EGLN3 | |
| SCHEMBL11388926 | 0.86 | CYP1A2 (0.36) | ALDH1A1TSHRATMHTTCYP1A2 | |
| Tetrazole SCHEMBL9733152 | 0.85 | KDM4E (0.36) | KDM4EGABRA1GABRB2GABRPGABRD | |
| SCHEMBL11356709 | 0.83 | CA1 (0.34) | HTTCYP1A2HSD11B1 | |
| SCHEMBL11398131 | 0.79 | CYP1A2 (0.34) | TSHRHTTCYP1A2HSD11B1 | |
| SCHEMBL10968077 | 0.79 | KDM4E (0.50) | KDM4EGABRA1GABRB2GABRPGABRD | |
| SCHEMBL829258 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296731-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-26 | — | — | EP | claimed |
| EP-0296731-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | claimed |
| EP-1728898-B1 | Electrolytes for the deposition of gold alloys | ROHM & HAAS ELECT MAT (US) | 2017-02-22 | — | — | EP | disclosed |
| US-8142637-B2 | Gold alloy electrolytes | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2012-03-27 | — | — | US | disclosed |
| US-20090104463-A1 | Gold alloy electrolytes | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2009-04-23 | — | — | US | disclosed |
| US-7465385-B2 | Gold alloy electrolytes | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-12-16 | — | — | US | disclosed |
| US-20060283714-A1 | Gold alloy electrolytes | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2006-12-21 | — | — | US | disclosed |
| EP-1728898-A2 | Electrolytes for the deposition of gold alloys | Rohm and Haas Electronic Materials LLC (US) | 2006-12-06 | — | — | EP | disclosed |
| US-5348952-A | Antibiotics for antiinflammatory agents, degenerative diseases caused by proteolytic enzymes and respiratory system disorders | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-09-20 | — | — | US | disclosed |
| EP-0505413-B1 | BETA-LACTAM DERIVATIVES | ERBA CARLO SPA (IT) | 1994-08-31 | — | — | EP | disclosed |
| US-5143931-A | 2-Phenyl-2((tetrazolyl or imidazolyl)thio)alkanoic acid derivatives; antiphylactic and bronchodilator agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-09-01 | — | — | US | disclosed |
| US-5135938-A | Bronchodilator | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-5066573-A | Sulfur containing compound which functions as a bleach accereration agent | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0296731-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4737452-A | WITH AROMATIC COMPOUND CONTAINING MERCAPTO AND HYDROZIDE GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| US-4550070-A | Direct positive silver halide photographic light-sensitive materials | FUJI PHOTO FILM CO., LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0154293-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1985-09-11 | — | — | EP | disclosed |
| US-4286089-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| US-4220644-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| US-4100346-A | Certain 7(o-amino-methyl- or methylaminomethylphenyl- or cyclohexadienyl- or thienylacetamide)-3[1-carboxymethyl-(or ethyl- or propyl-)-tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids | BRISTOL-MYERS COMPANY (US) | 1978-07-11 | — | — | US | disclosed |