Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.32 |
| ▸ | GABRP | O00591 | 5/20 | 0.32 |
| ▸ | GABRD | O14764 | 5/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.32 |
| ▸ | GABRE | P78334 | 5/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828869 | 0.85 | KDM4E (0.42) | KDM4EGABRA1GABRB2GABRPGABRD | |
| SCHEMBL11397997 | 0.79 | PTGS1 (0.41) | KDM4ETSHR | |
| SCHEMBL11388020 | 0.79 | PTGS1 (0.41) | KDM4ETSHR | |
| SCHEMBL11401238 | 0.79 | PTGS1 (0.41) | KDM4ETSHR | |
| SCHEMBL11388439 | 0.79 | PTGS1 (0.41) | KDM4ETSHR | |
| SCHEMBL829121 | 0.75 | EGLN3 (0.44) | KMOCYP1A2KDM4CHSD11B1EGLN3 | |
| SCHEMBL11388926 | 0.73 | CYP1A2 (0.36) | TSHRCYP1A2CYP2C9CYP2C19HSD11B1 | |
| Succinic Acid SCHEMBL1287285 | 0.72 | LMNA (0.41) | KDM4ETSHR | |
| Succinic Acid SCHEMBL1287287 | 0.72 | LMNA (0.41) | KDM4ETSHR | |
| SCHEMBL11356709 | 0.70 | CA1 (0.34) | CYP1A2CYP2C9CYP2C19HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143931-A | 2-Phenyl-2((tetrazolyl or imidazolyl)thio)alkanoic acid derivatives; antiphylactic and bronchodilator agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-09-01 | — | — | US | disclosed |