Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29287 | 0.80 | POLB (0.52) | KDM4ELMNACYP1A2POLBBLM | |
| SCHEMBL8540721 | 0.69 | ALDH1A1 (0.44) | KDM4ECYP1A2ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL28556777 | 0.67 | — | — | |
| SCHEMBL11608051 | 0.66 | MEN1 (0.42) | EHMT2EHMT1APOBEC3GKDM4ELMNA | |
| SCHEMBL11171846 | 0.66 | KDM4E (0.35) | EHMT2EHMT1APOBEC3GKDM4ELMNA | |
| SCHEMBL1029181 | 0.66 | HSD17B10 (0.52) | KDM4ECYP1A2POLBALDH1A1NPC1 | |
| SCHEMBL11154878 | 0.63 | MEN1 (0.36) | KDM4ELMNACYP1A2POLBALDH1A1 | |
| SCHEMBL11198611 | 0.62 | HSD17B10 (0.43) | EHMT2EHMT1APOBEC3GKDM4ELMNA | |
| SCHEMBL11133778 | 0.62 | MEN1 (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL4015315 | 0.60 | ALDH1A1 (0.67) | EHMT2EHMT1APOBEC3GKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248619-A | Bis[pyrimidyloxy(thio)]benzene derivatives | ICI AUSTRALIA LIMITED (AU) | 1981-02-03 | — | — | US | disclosed |