Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PRNP | P04156 | 5/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857102 | 0.77 | PRNP (0.49) | ALDH1A1PRNPRXFP1KDM4ENPSR1 | |
| SCHEMBL9294524 | 0.73 | ALDH1A1 (0.48) | ALDH1A1PRNPRXFP1KDM4EGRM5 | |
| SCHEMBL7207052 | 0.71 | EHMT2 (0.63) | ALDH1A1PRNPRXFP1KDM4EGRM5 | |
| SCHEMBL6899659 | 0.71 | RXFP1 (0.53) | ALDH1A1PRNPRXFP1KDM4ENPSR1 | |
| SCHEMBL2098479 | 0.71 | RXFP1 (0.53) | ALDH1A1PRNPRXFP1KDM4ENPSR1 | |
| SCHEMBL30562800 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KDM4EGRM5KCNH2MEN1 | |
| SCHEMBL11398814 | 0.69 | EHMT2 (0.36) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL11326601 | 0.67 | RXFP1 (0.50) | ALDH1A1PRNPRXFP1KDM4ENPSR1 | |
| SCHEMBL4370424 | 0.67 | RXFP1 (0.50) | ALDH1A1PRNPRXFP1KDM4ENPSR1 | |
| SCHEMBL10411067 | 0.67 | RXFP1 (0.50) | ALDH1A1PRNPRXFP1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497371-B1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI CHEMICALS INC (JP) | 1998-06-24 | — | — | EP | claimed |
| US-5202329-A | Pyrimidinyloxy(thio)quinoline derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-13 | — | — | US | claimed |
| EP-0497371-A1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | claimed |
| JP-6056823-A | — | — | None | — | — | JP | disclosed |
| JP-5271222-A | — | — | None | — | — | JP | disclosed |
| JP-5306203-A | — | — | None | — | — | JP | disclosed |
| JP-5301806-A | — | — | None | — | — | JP | disclosed |
| JP-5301805-A | — | — | None | — | — | JP | disclosed |
| EP-0497371-B1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI CHEMICALS INC (JP) | 1998-06-24 | — | — | EP | disclosed |
| EP-0497371-B1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI CHEMICALS INC (JP) | 1998-06-24 | — | — | EP | disclosed |
| JP-H0656823-A | QUINOLINE DERIVATIVE HAVING ALKYLTHIO GROUP IN PYRIMIDINE RING, ITS PRODUCTION AND GERMICIDE FOR AGRICULTURE AND HORTICULTURE CONTAINING THE SAME DERIVATIVE AS ACTIVE INGREDIENT | MITSUI TOATSU CHEM INC | 1994-03-01 | — | — | JP | disclosed |
| JP-H05301805-A | FUNGICIDAL COMPOSITION FOR AGRICULTURAL AND HORTICULTURAL PURPOSES | MITSUI TOATSU CHEM INC | 1993-11-16 | — | — | JP | disclosed |
| JP-H05301806-A | FUNGICIDAL COMPOSITION FOR AGRICULTURAL AND HORTICULTURAL PURPOSES | MITSUI TOATSU CHEM INC | 1993-11-16 | — | — | JP | disclosed |
| JP-H05271222-A | PYRIMIDINYLOXY@(3754/24)THIO)QUINOLINE DERIVATIVE, ITS PRODUCTION AND AGRICULTURAL AND HORTICULTURAL GERMICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | MITSUI TOATSU CHEM INC | 1993-10-19 | — | — | JP | disclosed |
| US-5202329-A | Pyrimidinyloxy(thio)quinoline derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-5202329-A | Pyrimidinyloxy(thio)quinoline derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-5202329-A | Pyrimidinyloxy(thio)quinoline derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0497371-A1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | disclosed |
| EP-0497371-A1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | disclosed |
| EP-0497371-A1 | Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | disclosed |