Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399159 | 1.00 | NAMPT (0.51) | NAMPTGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL11720041 | 0.85 | MAPT (0.48) | NAMPTKMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7528187 | 0.85 | MAPT (0.62) | NAMPTKMT2AMAPTALDH1A1PPID | |
| SCHEMBL11720022 | 0.85 | MAPT (0.48) | NAMPTKMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL6734945 | 0.85 | MAPT (0.62) | NAMPTKMT2AMAPTALDH1A1PPID | |
| SCHEMBL11726774 | 0.83 | MEN1 (0.50) | KMT2AMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL11726763 | 0.83 | MEN1 (0.50) | KMT2AMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL18618468 | 0.82 | ALDH1A1 (0.56) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL21124311 | 0.82 | PPID (0.46) | NAMPTGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL29450231 | 0.82 | ALDH1A1 (0.56) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273573-A | Agents for regulating plant growth using 2-thiazolone-5-carboxylic acid compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-16 | — | — | US | disclosed |