Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19220754 | 0.82 | FBP1 (0.38) | FBP1PDE7A | |
| SCHEMBL2432241 | 0.78 | FBP1 (0.68) | FBP1PDE7APTGS2DDB1CRBN | |
| SCHEMBL588852 | 0.77 | FBP1 (0.54) | FBP1PDE7APTGS2 | |
| Hydrogen Sulfide SCHEMBL2786811 | 0.76 | FBP1 (0.52) | FBP1PDE7APTGS2 | |
| SCHEMBL31351864 | 0.76 | FBP1 (0.52) | FBP1PDE7APTGS2DDB1CRBN | |
| SCHEMBL6665571 | 0.75 | CYP2A6 (0.38) | CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL2787500 | 0.72 | NR1H2 (0.52) | FBP1PDE7ADDB1CRBN | |
| SCHEMBL4585229 | 0.72 | FBP1 (0.48) | FBP1PDE7A | |
| SCHEMBL6772507 | 0.72 | FBP1 (0.48) | FBP1PDE7ADDB1CRBN | |
| SCHEMBL6778047 | 0.72 | FBP1 (0.48) | FBP1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294838-A | ANTIBRONCHOSPASMOLYTIC AGENTS | WARNER-LAMBERT COMPANY, A CORP. OF DE | 1981-10-13 | — | — | US | disclosed |