Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20932431 | 0.76 | IDO1 (0.49) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30384601 | 0.72 | MAPT (0.53) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL3501667 | 0.72 | MAPT (0.53) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL2491027 | 0.72 | KDM4E (0.53) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL1258591 | 0.72 | MAPT (0.53) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL24584368 | 0.72 | NQO2 (0.57) | MAPTALDH1A1KDM4ETDP1NQO2 | |
| Phenazine SCHEMBL29356959 | 0.71 | MAPT (1.00) | MAPTALDH1A1HPGDKDM4EGAA | |
| Phenazine SCHEMBL9049 | 0.71 | MAPT (1.00) | MAPTALDH1A1HPGDKDM4EGAA | |
| Phenazine SCHEMBL27643128 | 0.71 | MAPT (1.00) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL14493277 | 0.69 | MAPT (0.58) | MAPTALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264600-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4252954-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| EP-0010426-A1 | Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |