Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28585108 | 0.97 | KDM4E (0.52) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL28608867 | 0.95 | KDM4E (0.50) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3735430 | 0.85 | LMNA (0.53) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL12858948 | 0.85 | KDM4E (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10175661 | 0.84 | KDM4E (0.46) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL31193100 | 0.84 | KDM4E (0.46) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL11918970 | 0.84 | KDM4E (0.58) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10009532 | 0.84 | TDP1 (0.58) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL14425574 | 0.82 | NQO2 (0.54) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL18721598 | 0.80 | KDM4E (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383762-A1 | TETRAHYDROPYRIDYL-ALKYL-HETEROCYCLES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-01-28 | — | — | EP | claimed |
| WO-2002085888-A1 | TETRAHYDROPYRIDYL-ALKYL-HETEROCYCLES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-10-31 | — | — | WO | claimed |
| CN-117945995-A | Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof | 中国科学院青海盐湖研究所 | 2024-04-30 | — | — | CN | disclosed |
| WO-2018045090-A1 | BISPECIFIC ANTIBODIES | IMMUNOMAB, INC. (US) | 2018-03-08 | — | — | WO | disclosed |
| US-9841652-B2 | Electrochromic composition | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2017-12-12 | — | — | US | disclosed |
| US-9785030-B2 | Electrochromic composition | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2017-10-10 | — | — | US | disclosed |
| US-20160231636-A1 | ELECTROCHROMIC COMPOSITION | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2016-08-11 | — | — | US | disclosed |
| WO-2014145095-A1 | MACROCYCLIC AND BICYCLIC INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014008285-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. (US) | 2014-01-09 | — | — | WO | disclosed |
| US-20130027636-A1 | CLASS OF BRIDGED BIPHENYLENE POLYMERS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2013-01-31 | — | — | US | disclosed |
| US-8330039-B2 | Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100180947-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| US-7705014-B2 | Inhibitors of AKT activity | MERCK SHARP & DOHME CORP. (US) | 2010-04-27 | — | — | US | disclosed |
| US-7589068-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-20090062327-A1 | Inhibitors of AKT Activity | MERCK SHARP & DOHME CORP. | 2009-03-05 | — | — | US | disclosed |
| US-20090036622-A1 | High Bandgap Arylene Polymers | SUMATION CO. LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20080009507-A1 | Inhibitors of Akt Activity | MERCK SHARP & DOHME CORP. | 2008-01-10 | — | — | US | disclosed |
| US-7223738-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-4303689-A | Flavoring with pyrazine derivatives | FIRMENICH SA (CH) | 1981-12-01 | — | — | US | disclosed |
| US-4138410-A | Flavoring agent | FIRMENICH & CIE (CH) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062327-A1 | Inhibitors of AKT Activity | PIK3CD, PIK3CA, PIK3CG | KDM4E 1661/4885MAPT 4460/4885ALDH1A1 3853/4885 |
| US-20090036622-A1 | High Bandgap Arylene Polymers | PARG, PCBP1, PARN | KDM4E 2715/4885MAPT 679/4885ALDH1A1 1273/4885 |
| US-20080009507-A1 | Inhibitors of Akt Activity | PIK3CD, PIK3CA, PIK3CG | KDM4E 1661/4885MAPT 4460/4885ALDH1A1 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.