Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.95 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.87 |
| ▸ | PDE4A | P27815 | 6/20 | 0.87 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.87 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.87 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.87 |
| ▸ | BRD4 | O60885 | 4/20 | 0.82 |
| ▸ | BRD2 | P25440 | 2/20 | 0.82 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.82 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457891 | 0.97 | MEN1 (1.00) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL7031729 | 0.90 | MEN1 (0.87) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL19066317 | 0.90 | BRD4 (1.00) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL11394726 | 0.89 | MEN1 (0.80) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL11395669 | 0.88 | MEN1 (0.78) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL11399416 | 0.88 | MEN1 (0.78) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL11401591 | 0.88 | MEN1 (0.81) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL27552709 | 0.87 | MEN1 (0.73) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL1713301 | 0.86 | MEN1 (0.71) | MEN1KMT2AALDH1A1ADORA2APDE4A | |
| SCHEMBL25286006 | 0.86 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1ADORA2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289776-A | VASODILATORS, FIBRINOLYTIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |