Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429395 | 0.78 | MAOB (0.46) | MAOBFFAR1FFAR4 | |
| SCHEMBL11388004 | 0.78 | MAOB (0.55) | MAOBFFAR1FFAR4CCNB2CDK1 | |
| SCHEMBL11399725 | 0.76 | HTR1A (0.45) | KDM4ETHRBHPGD | |
| SCHEMBL11399750 | 0.76 | HTR1A (0.45) | KDM4ETHRBHPGD | |
| SCHEMBL11388723 | 0.76 | NR1H4 (0.51) | MAOBFFAR1FFAR4KDM4EPPARG | |
| SCHEMBL11388721 | 0.76 | NR1H4 (0.51) | MAOBFFAR1FFAR4KDM4EPPARG | |
| SCHEMBL11399724 | 0.76 | HTR1A (0.45) | KDM4ETHRBHPGD | |
| SCHEMBL11401575 | 0.75 | MAOB (0.52) | MAOBFFAR1FFAR4CCNB2CDK1 | |
| SCHEMBL11388895 | 0.74 | ABCB1 (0.44) | — | |
| SCHEMBL11388893 | 0.74 | ABCB1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262013-A | ANTILIPEMIC AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | disclosed |
| US-4198425-A | ANTILIPEMIC AGENTS | SANKYO COMPANY LIMITED (JP) | 1980-04-15 | — | — | US | disclosed |