SCHEMBL11399643

SCHEMBL11399643

CCCCCCNNS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.57
CYP2C9 P11712 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
LMNA P02545 3/20 0.52
ALB P02768 1/20 0.52
TSHR P16473 1/20 0.52
KMT2A Q03164 3/20 0.49
RAB9A P51151 1/20 0.49
KDM4E B2RXH2 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2D6 P10635 2/20 0.49
HPGD P15428 2/20 0.49
ALOX12 P18054 2/20 0.49
CYP2C19 P33261 2/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
APOBEC3G Q9HC16 1/20 0.49
MCHR1 Q99705 1/20 0.48
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22499521 0.85 ALDH1A1 (0.56) ALDH1A1TDP1LMNATSHRKDM4E
SCHEMBL634180 0.83 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AKDM4EALOX12
SCHEMBL223156 0.83 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AKDM4EALOX12
SCHEMBL28034898 0.83 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AKDM4EALOX12
SCHEMBL634183 0.83 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AKDM4EALOX12
SCHEMBL5696735 0.83 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AKDM4EALOX12
SCHEMBL633648 0.83 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AKDM4EALOX12
SCHEMBL8355315 0.83 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AKDM4EALOX12
SCHEMBL7103280 0.83 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AKDM4EALOX12
SCHEMBL9234209 0.83 ALDH1A1 (0.53) ALDH1A1TDP1LMNATSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4301129-A BY TREATING AN INORGANIC CYANIDE WITH A BORON TRIFLUORIDE DONOR THIOKOL CORPORATION (US) 1981-11-17 US disclosed
EP-0009382-A1 Production of cyanoborohydrides THIOKOL CORPORATION (US) 1980-04-02 EP disclosed