SCHEMBL28034898

SCHEMBL28034898

CCCCCCCCCCCCCCNS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.72

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.72
CA12 O43570 1/20 0.64
CA2 P00918 1/20 0.64
CA9 Q16790 1/20 0.64
HTT P42858 2/20 0.62
ALOX15 P16050 1/20 0.62
LMNA P02545 4/20 0.61
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
MAPK1 P28482 1/20 0.60
PKM P14618 3/20 0.59
KDM4E B2RXH2 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MBTD1 Q05BQ5 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
ALOX12 P18054 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL635949 1.00 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT
SCHEMBL633648 1.00 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT
SCHEMBL634180 1.00 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT
SCHEMBL634183 1.00 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT
SCHEMBL8355315 1.00 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT
SCHEMBL5696735 1.00 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT
SCHEMBL7103280 1.00 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT
SCHEMBL223156 1.00 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT
SCHEMBL635208 0.98 ALDH1A1 (0.70) ALDH1A1CA12CA2CA9HTT
SCHEMBL187922 0.93 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106565549-A Method of synthesis of N-alkyl p-toluene sulfonamide 南安创友日化有限公司 2017-04-19 CN disclosed
CN-104892470-B Method for preparing N-alkyl-p-toluenesulfonamide 嘉兴学院 2017-04-12 CN disclosed
CN-104892470-A Method for preparing N-alkyl-p-toluenesulfonamide UNIV JIAXING 2015-09-09 CN disclosed