⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585609 | 0.71 | — | — | |
| SCHEMBL28619192 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL29067640 | 0.69 | — | — | |
| SCHEMBL4608600 | 0.67 | — | — | |
| SCHEMBL28151024 | 0.67 | — | — | |
| SCHEMBL24828275 | 0.67 | — | — | |
| SCHEMBL28154457 | 0.67 | — | — | |
| SCHEMBL8174055 | 0.67 | — | — | |
| SCHEMBL28833108 | 0.66 | ALPL (0.59) | — | |
| SCHEMBL27921698 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256902-A | FORMING AN ALKALINE SALT BY REACTING A HYDRAZINE WITH A B,B-DICHLORO-ACRYLOYL CHLORIDE, ACIDIFYING | MONTEDISON S.P.A. (IT) | 1981-03-17 | — | — | US | claimed |
| CN-102271515-B | Pyrazolopyrimidine jak inhibitor compounds and methods | GENENTECH INC | 2014-07-02 | — | — | CN | disclosed |
| US-4256902-A | FORMING AN ALKALINE SALT BY REACTING A HYDRAZINE WITH A B,B-DICHLORO-ACRYLOYL CHLORIDE, ACIDIFYING | MONTEDISON S.P.A. (IT) | 1981-03-17 | — | — | US | disclosed |