Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844788 | 0.80 | CA12 (0.59) | ALPLCA12KMT2AMEN1NPC1 | |
| SCHEMBL20583624 | 0.80 | SMN1; SMN2 (0.61) | ALPLCA12KMT2AMEN1NPC1 | |
| SCHEMBL643623 | 0.79 | RAB9A (0.61) | ALPLCA12KMT2AMEN1NPC1 | |
| SCHEMBL9048096 | 0.78 | KMT2A (0.64) | ALPLCA12KMT2AMEN1NPC1 | |
| SCHEMBL28195531 | 0.77 | NOTUM (0.44) | ALPLCA12KMT2AMEN1NPC1 | |
| Bromide SCHEMBL31659833 | 0.77 | KMT2A (0.62) | ALPLCA12KMT2AMEN1NPC1 | |
| Bromide SCHEMBL26095595 | 0.77 | KMT2A (0.62) | ALPLCA12KMT2AMEN1NPC1 | |
| SCHEMBL474802 | 0.76 | ALPL (0.54) | ALPLCA12KMT2AMEN1NPC1 | |
| SCHEMBL22593932 | 0.76 | ALPL (0.54) | ALPLCA12KMT2AMEN1NPC1 | |
| SCHEMBL1160360 | 0.76 | NPC1 (0.67) | ALPLCA12KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104059020-B | The preparation method of 1-aryl-5-hydroxypyrazoles | 湖南海利常德农药化工有限公司 | 2016-08-31 | — | — | CN | disclosed |