Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863333 | 0.80 | MAPT (0.49) | MAPTHTTALDH1A1TSHRKDM4E | |
| SCHEMBL11397475 | 0.78 | MAPT (0.44) | MAPTHTTTSHREGFRPPARD | |
| SCHEMBL11401392 | 0.78 | ALDH1A1 (0.41) | ALDH1A1EGFR | |
| SCHEMBL8864052 | 0.77 | MAPT (0.43) | MAPTHTTALDH1A1TSHRKDM4E | |
| SCHEMBL11392501 | 0.76 | MAPT (0.43) | MAPTHTTALDH1A1TSHR | |
| SCHEMBL9372048 | 0.75 | HMGCR (0.34) | MAPTHTTHMGCR | |
| SCHEMBL9327051 | 0.75 | HMGCR (0.42) | HMGCRALDH1A1NR1I2 | |
| SCHEMBL11387029 | 0.75 | MAPT (0.42) | MAPTHTTTSHREGFR | |
| SCHEMBL9309393 | 0.74 | MAPT (0.41) | MAPTHTTALDH1A1TSHR | |
| SCHEMBL11400724 | 0.74 | MAPT (0.50) | MAPTHTTALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251539-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-02-17 | — | — | US | disclosed |