Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.34 |
| ▸ | CDK9 | P50750 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863333 | 0.81 | MAPT (0.49) | MAPTHTTTSHREGFRALDH1A1 | |
| SCHEMBL11397475 | 0.79 | MAPT (0.44) | MAPTHTTTSHREGFR | |
| SCHEMBL11387029 | 0.79 | MAPT (0.42) | MAPTHTTTSHREGFR | |
| SCHEMBL6608431 | 0.79 | CHRM1 (0.36) | CHRM1ALDH1A1KDM4E | |
| SCHEMBL11392501 | 0.77 | MAPT (0.43) | MAPTHTTTSHRALDH1A1 | |
| SCHEMBL11399889 | 0.77 | MAPT (0.43) | MAPTHTTTSHREGFRALDH1A1 | |
| SCHEMBL9863391 | 0.77 | NOTUM (0.51) | MAPTHTTALDH1A1 | |
| SCHEMBL8911499 | 0.76 | CHRM1 (0.41) | MAPTCHRM1 | |
| SCHEMBL9309393 | 0.75 | MAPT (0.41) | MAPTHTTTSHRALDH1A1 | |
| SCHEMBL11400724 | 0.75 | MAPT (0.50) | MAPTHTTTSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637712-A | CATALYTIC HYDROGENNATION | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | disclosed |