Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PLAT | P00750 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KLK8 | O60259 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | KLK2 | P20151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400014 | 0.82 | ELANE (0.42) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL11390684 | 0.82 | ELANE (0.45) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL11388126 | 0.78 | NPSR1 (0.42) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL10458711 | 0.77 | ANPEP (0.41) | ELANETP53KLK1PLAUF2 | |
| SCHEMBL11798198 | 0.76 | CYP3A4 (0.40) | LMNAALDH1A1GAA | |
| SCHEMBL11795463 | 0.74 | RAB9A (0.43) | ELANEKLK1PLAUF2PLAT | |
| SCHEMBL6996344 | 0.66 | CHRM1 (0.51) | TP53KMT2ALMNAALDH1A1 | |
| SCHEMBL11432653 | 0.63 | SRC (0.48) | PLAUMEN1KMT2ALMNARECQL | |
| SCHEMBL575458 | 0.63 | ATM (0.41) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL11390682 | 0.62 | ELANE (0.50) | ELANETP53KLK1PLAUF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947413-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-03-30 | — | — | US | disclosed |