Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397194 | 0.83 | NPC1 (0.46) | KDM4EPOLBTDP1L3MBTL1AKR1C3 | |
| SCHEMBL11397431 | 0.82 | MEN1 (0.47) | POLBTDP1AKR1C2NOTUMCSNK2A1 | |
| SCHEMBL11399691 | 0.79 | MEN1 (0.47) | NOTUMCSNK2A2CSNK2BCSNK2A1MAPK8 | |
| SCHEMBL11395038 | 0.79 | EPHX1 (0.40) | KDM4ENOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11397466 | 0.77 | ACMSD (0.42) | KDM4EDHODHCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5030912 | 0.76 | EDNRA (0.55) | EDNRAKDM4EPOLBHSP90AA1MTNR1A | |
| SCHEMBL30407941 | 0.76 | EDNRA (0.52) | EDNRAKDM4EPOLBHSP90AA1MTNR1A | |
| SCHEMBL11402993 | 0.76 | MEN1 (0.43) | KDM4EPOLBL3MBTL1NOTUMMAPK8 | |
| SCHEMBL7078258 | 0.74 | DHODH (0.54) | KDM4EPOLBTDP1L3MBTL1DHODH | |
| SCHEMBL11401949 | 0.73 | EDNRA (0.50) | EDNRAKDM4EPOLBHSP90AA1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |