Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400326 | 0.83 | EDNRA (0.52) | POLBKDM4ETDP1L3MBTL1MAPK8 | |
| SCHEMBL11397647 | 0.83 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL11395207 | 0.80 | RHEB (0.39) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL11398653 | 0.80 | HAO1 (0.42) | RAB9AALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL9825879 | 0.77 | KMT2A (0.52) | ALDH1A1KMT2ACA1CA2SMN1; SMN2 | |
| SCHEMBL11397466 | 0.76 | ACMSD (0.42) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL9828861 | 0.76 | FBP1 (0.45) | MEN1KMT2ACA1CA2KDR | |
| SCHEMBL7076248 | 0.74 | SMN1; SMN2 (0.54) | NPC1RAB9AALDH1A1CA1CA2 | |
| SCHEMBL9829539 | 0.74 | FBP1 (0.44) | NPC1RAB9AALDH1A1MEN1HTT | |
| SCHEMBL9829325 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CA1CA2KDRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |