SCHEMBL11400367

SCHEMBL11400367

Cc1ccc2c(c1C)C(=O)c1c(C)c(C)cc(C)c1C2=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.61
NSD2 O96028 1/20 0.61
HSP90AA1 P07900 1/20 0.61
PAX8 Q06710 1/20 0.61
ELANE P08246 6/20 0.44
CTSG P08311 1/20 0.41
CYP3A4 P08684 4/20 0.41
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
NPC1 O15118 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
HBB P68871 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
EPHX2 P34913 1/20 0.35
MAPT P10636 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10602533 0.86 TDP2 (0.68) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL27507563 0.85 TDP2 (0.81) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL16980234 0.83 TDP2 (0.42) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL11398357 0.82 TDP2 (0.38) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL24602919 0.81 TDP2 (0.73) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL3205133 0.80 TDP2 (0.65) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL6905929 0.80 ELANE (0.52) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL11399582 0.79 MAOA (0.57) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL13387891 0.77 TDP2 (0.61) TDP2NSD2HSP90AA1PAX8ELANE
SCHEMBL29536368 0.77 TDP2 (0.61) TDP2NSD2HSP90AA1PAX8ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4277546-A Sealed lead-acid storage battery BARSUKOV VYACHESLAV Z 1981-07-07 US disclosed