Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.62 |
| ▸ | DRD2 | P14416 | 4/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11401361 | 0.99 | DRD3 (0.60) | DRD3DRD2CHRM2HTR1AHTR2B | |
| SCHEMBL13018937 | 0.86 | DRD3 (0.61) | DRD3DRD2CHRM2HTR1AHTR2B | |
| SCHEMBL10057681 | 0.83 | DRD2 (0.63) | DRD3DRD2CHRM2HTR1AHTR2B | |
| SCHEMBL11393853 | 0.82 | DRD2 (0.59) | DRD3DRD2HTR2CPRKDC | |
| Hydrochloric Acid SCHEMBL11397089 | 0.81 | DRD2 (0.58) | DRD3DRD2HTR2CPRKDC | |
| SCHEMBL28701675 | 0.81 | DRD3 (0.48) | DRD3DRD2CHRM2HTR1AHTR2B | |
| SCHEMBL7323009 | 0.80 | DRD3 (0.66) | DRD3DRD2HTR1A | |
| SCHEMBL21323287 | 0.78 | DRD2 (0.63) | DRD3DRD2 | |
| SCHEMBL2603277 | 0.78 | DRD2 (0.63) | DRD3DRD2 | |
| SCHEMBL17658922 | 0.78 | DRD2 (0.63) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259337-A | ANTIDEPRESSANTS, ANOREXIGENIC AGENTS ANTIPARKINSONIAN ACTIVITY | ROUSSEL UCLAF (FR) | 1981-03-31 | — | — | US | disclosed |