⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16239625 | 0.98 | NAMPT (0.45) | — | |
| Water SCHEMBL29957253 | 0.98 | NAMPT (0.45) | — | |
| SCHEMBL2574438 | 0.98 | NAMPT (0.45) | — | |
| SCHEMBL5604635 | 0.84 | TSHR (0.49) | — | |
| SCHEMBL368414 | 0.83 | NAMPT (0.44) | — | |
| SCHEMBL12234495 | 0.82 | — | — | |
| Bromide SCHEMBL7373319 | 0.82 | RAB9A (0.48) | — | |
| SCHEMBL405925 | 0.82 | — | — | |
| SCHEMBL711909 | 0.80 | — | — | |
| SCHEMBL284637 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 848 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | claimed |
| EP-3551632-B1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | UNION THERAPEUTICS AS (DK) | 2024-06-12 | — | — | EP | claimed |
| CN-117903059-A | Preparation method of ligand compound | 浙江瑞博制药有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-109912577-B | Compound for inhibiting tumor related to EB virus and preparation method and application thereof | 深圳先进技术研究院 | 2021-10-22 | — | — | CN | claimed |
| CN-112359594-A | Medical fiber material, preparation method and application thereof | 嘉兴市爵拓科技有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-109970720-B | Aurora A protein inhibitor and preparation method and pharmaceutical application thereof | 深圳先进技术研究院 | 2020-07-03 | — | — | CN | claimed |
| EP-2785695-B1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-06-17 | — | — | EP | claimed |
| CN-106674209-B | Programmed death receptor 1 gene inhibitor and preparation method and application thereof | 深圳先进技术研究院 | 2020-03-06 | — | — | CN | claimed |
| EP-2755963-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2019-10-30 | — | — | EP | claimed |
| CN-109970617-A | A series of oligomerization amides and its synthetic method containing N- methylpyrrole and N- methylimidazole | 上海茂晟康慧科技有限公司 | 2019-07-05 | — | — | CN | claimed |
| US-20060199846-A1 | Certain substituted ureas as modulators of kinase activity | GILEAD CONNECTICUT, INC. | 2006-09-07 | — | — | US | claimed |
| EP-1680124-A2 | BICYCLIC [3.1.0] DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS | Pfizer Products Incorporated (US) | 2006-07-19 | — | — | EP | claimed |
| WO-2006051063-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO | FERRER INTERNACIONAL S. A. (ES) | 2006-05-18 | — | — | WO | claimed |
| US-20060052365-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-03-09 | — | — | US | claimed |
| JP-2006505526-A | — | — | 2006-02-16 | — | — | JP | claimed |
| WO-2005121145-A2 | OCTAHYDRO-PYRROLO[3,4-C] DERIVATIVES AND THEIR USE AS ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-22 | — | — | WO | claimed |
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | claimed |
| US-20050096375-A1 | Bicyclic [3.1.0] derivatives as glycine transporter inhibitors | PFIZER INC. | 2005-05-05 | — | — | US | claimed |
| WO-2005037216-A2 | BICYCLIC [3.1.0] DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-04-28 | — | — | WO | claimed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | claimed |