⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5464242 | 0.98 | NAMPT (0.44) | — | |
| Lithium SCHEMBL31348018 | 0.98 | NAMPT (0.44) | — | |
| Formic Acid SCHEMBL25412985 | 0.92 | NAMPT (0.41) | — | |
| Biphenyl SCHEMBL27844503 | 0.88 | TSHR (0.46) | — | |
| Trifluoroacetic Acid SCHEMBL27785531 | 0.88 | L3MBTL1 (0.40) | — | |
| SCHEMBL5604635 | 0.82 | TSHR (0.49) | — | |
| SCHEMBL12234495 | 0.80 | — | — | |
| SCHEMBL405925 | 0.80 | — | — | |
| Bromide SCHEMBL7373319 | 0.80 | RAB9A (0.48) | — | |
| SCHEMBL114011 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317708-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-09-26 | — | — | US | claimed |
| CN-114981259-B | Novel heterocyclic compound | 豪夫迈·罗氏有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118119609-A | Imidazole derivatives and their use as antibiotics | 豪夫迈·罗氏有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117715892-A | Quaternary ammonium cation substituted compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-03-15 | — | — | CN | claimed |
| EP-3694502-B1 | NOVEL SUBSTITUTED CYCLOBUTYLBENZENE COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-08-02 | — | — | EP | claimed |
| EP-4211116-A1 | NOVEL HETEROCYCLIC ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2023-07-19 | — | — | EP | claimed |
| EP-4208454-A1 | IMIDAZOLE-PYRAZOLE DERIVATIVES WITH ANTI-BACTERIAL PROPERTIES | F. Hoffmann-La Roche AG (CH) | 2023-07-12 | — | — | EP | claimed |
| EP-4204090-A1 | IMIDAZOLE-PYRAZOLE DERIVATIVES AS ANTIBACTERIALS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | claimed |
| CN-116096709-A | Novel heterocyclic antibiotics | 豪夫迈·罗氏有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-115989227-A | Imidazole-pyrazole derivatives having antibacterial properties | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | claimed |
| WO-2022049272-A1 | NOVEL HETEROCYCLIC ANTIBIOTICS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-03-10 | — | — | WO | claimed |
| WO-2022049011-A1 | IMIDAZOLE-PYRAZOLE DERIVATIVES WITH ANTI-BACTERIAL PROPERTIES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-03-10 | — | — | WO | claimed |
| WO-2022043486-A1 | IMIDAZOLE-PYRAZOLE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-03-03 | — | — | WO | claimed |
| EP-3934756-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2022-01-12 | — | — | EP | claimed |
| CN-112920169-A | N-indolyl imidazole carboxamide compound and preparation method and application thereof | 中国医科大学 | 2021-06-08 | — | — | CN | claimed |
| WO-2020182648-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-09-17 | — | — | WO | claimed |
| EP-1732896-B1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMA INC (US) | 2012-12-12 | — | — | EP | claimed |
| US-20090247559-A1 | Benzofuropyrimidinones | EXELIXIS, INC. (US) | 2009-10-01 | — | — | US | claimed |
| US-20040038973-A1 | Treating osteoarthritis or rheumatoid arthritis | NAHRA JOE (US) | 2004-02-26 | — | — | US | claimed |
| WO-2004014365-A1 | PHTHALIMIDE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |