Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963353 | 0.96 | PTPRZ1 (0.63) | PTPRZ1PTPN1NR1H4EPHX2CA2 | |
| Ethane SCHEMBL11271912 | 0.88 | PTPRZ1 (0.46) | PTPRZ1CA2CAMK2ARXRARXRB | |
| SCHEMBL13169964 | 0.84 | PTPRZ1 (0.61) | PTPRZ1PTPN1NR1H4EPHX2ALDH1A1 | |
| SCHEMBL11444608 | 0.81 | PTPRZ1 (0.44) | PTPRZ1CA2CAMK2ARXRARXRB | |
| SCHEMBL10655795 | 0.81 | PTPRZ1 (0.58) | PTPRZ1PTPN1NR1H4EPHX2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11269350 | 0.80 | PTPRZ1 (0.43) | PTPRZ1CA2CAMK2ARXRARXRB | |
| SCHEMBL9108524 | 0.80 | PTPRZ1 (0.61) | PTPRZ1PTPN1NR1H4EPHX2CA2 | |
| SCHEMBL13946807 | 0.79 | PTPRZ1 (0.60) | PTPRZ1PTPN1NR1H4EPHX2ALDH1A1 | |
| SCHEMBL8362761 | 0.77 | CA2 (0.58) | CA2CAMK2AAKR1B1ALDH1A1HPGD | |
| SCHEMBL2646892 | 0.76 | NR1H4 (0.51) | PTPRZ1PTPN1NR1H4RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284643-A | Combating arthropods with novel fluorine-containing phenylacetic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |