Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105263 | 1.00 | ATM (0.46) | ATML3MBTL1ALOX15ADRB2ADRB1 | |
| SCHEMBL27660502 | 0.85 | ATM (0.44) | ATML3MBTL1ALOX15ADRB2ADRB1 | |
| SCHEMBL5198959 | 0.82 | ATM (0.47) | ATML3MBTL1ALOX15ADRB2ADRB1 | |
| SCHEMBL27551102 | 0.81 | ATM (0.46) | ATML3MBTL1ALOX15ELANETDP1 | |
| SCHEMBL29163224 | 0.81 | ATM (0.46) | ATML3MBTL1ALOX15ADRB2ADRB1 | |
| SCHEMBL24530374 | 0.81 | ATM (0.46) | ATML3MBTL1ALOX15ELANETDP1 | |
| SCHEMBL2619547 | 0.81 | ATM (0.50) | ATML3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL27639690 | 0.81 | ATM (0.46) | ATML3MBTL1ALOX15ELANETDP1 | |
| SCHEMBL15156036 | 0.80 | CCNC (0.46) | ALOX15TDP1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL6182569 | 0.79 | CYP1A2 (0.47) | ATML3MBTL1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575929-B1 | THE METHOD FOR PRODUCTION OF SEMI-FINISHED PRODUCTS USEFUL IN SYNTHESIS OF PACLITAXEL | AGROPHARM S A (PL) | 2007-03-21 | — | — | EP | claimed |
| EP-1575929-A1 | THE METHOD FOR PRODUCTION OF SEMI-FINISHED PRODUCTS USEFUL IN SYNTHESIS OF PACLITAXEL | Agropharm S.A. (PL) | 2005-09-21 | — | — | EP | claimed |
| WO-2004056790-A1 | THE METHOD FOR PRODUCTION OF SEMI-FINISHED PRODUCTS USEFUL IN SYNTHESIS OF PACLITAXEL | AGROPHARM S.A. (PL) | 2004-07-08 | — | — | WO | claimed |
| JP-3083956-A | — | — | None | — | — | JP | disclosed |
| CN-105008419-B | Photochromic curable composition, cured product thereof, and laminate containing same | 株式会社德山 | 2016-10-12 | — | — | CN | disclosed |
| CN-105037243-A | Paclitaxel side-chain phenyl serine derivative, and preparation method and application thereof | UNIV GUIZHOU | 2015-11-11 | — | — | CN | disclosed |
| CN-105008419-A | Photochromic curable composition, cured product thereof, and laminate containing same | TOKUYAMA CORP | 2015-10-28 | — | — | CN | disclosed |
| US-8299279-B2 | Semi-synthetic process for the preparation of taxane derivatives | CHATHAM BIOTEC LTD. (CA) | 2012-10-30 | — | — | US | disclosed |
| EP-1383754-B1 | PROCESS FOR MAKING TAXANE DERIVATIVES | SCINOPHARM TAIWAN LTD (TW) | 2011-02-23 | — | — | EP | disclosed |
| US-20100029957-A1 | Semi-Synthetic Process for the Preparation of Taxane Derivatives | CHATHAM BRUNSWICK BIOTEC LTD (CA) | 2010-02-04 | — | — | US | disclosed |
| EP-2114908-A1 | SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF TAXANE DERIVATIVES | Chatham Biotec Ltd (CA) | 2009-11-11 | — | — | EP | disclosed |
| EP-0690853-A4 | TAXANES PREPARED BY BETA-LACTAMS AND AMMONIUM ALKOXIDES | UNIV FLORIDA STATE (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0690853-A1 | TAXANES PREPARED BY BETA-LACTAMS AND AMMONIUM ALKOXIDES | FLORIDA STATE UNIVERSITY (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5466834-A | Taxane antitumor agent | FLORIDA STATE UNIVERSITY (US) | 1995-11-14 | — | — | US | disclosed |
| US-5430160-A | Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides | FLORIDA STATE UNIVERSITY (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1994021623-A1 | TAXANES PREPARED BY BETA-LACTAMS AND AMMONIUM ALKOXIDES | FLORIDA STATE UNIVERSITY (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0605637-A4 | PREPARATION OF SUBSTITUTED ISOSERINE ESTERS USING METAL ALKOXIDES AND -G(B)-LACTAMS. | UNIV FLORIDA STATE (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0605637-A1 | PREPARATION OF SUBSTITUTED ISOSERINE ESTERS USING METAL ALKOXIDES AND $g(b)-LACTAMS | FLORIDA STATE UNIVERSITY (US) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993006079-A1 | PREPARATION OF SUBSTITUTED ISOSERINE ESTERS USING METAL ALKOXIDES AND β-LACTAMS | FLORIDA STATE UNIVERSITY (US) | 1993-04-01 | — | — | WO | disclosed |
| JP-H0383956-A | ENANTHIO-SELECTIVE PREPARATION OF PHENYL ISOSERINE DERIVATIVE | CENTRE NATL RECH SCIENT (CNRS) | 1991-04-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029957-A1 | Semi-Synthetic Process for the Preparation of Taxane Derivatives | WEE1, WEE2, NOTUM | ATM 996/4885L3MBTL1 3609/4885ALOX15 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.