Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847820 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2HSD17B10CES2CES1LMNA | |
| SCHEMBL9436669 | 0.84 | CES2 (0.44) | SMN1; SMN2HSD17B10CES2CES1LMNA | |
| Formic Acid SCHEMBL2161063 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2HSD17B10CES2CES1LMNA | |
| Alcohol SCHEMBL27732747 | 0.82 | CES2 (0.46) | SMN1; SMN2CES2CES1LMNAPLG | |
| SCHEMBL813277 | 0.82 | CES2 (0.38) | SMN1; SMN2HSD17B10CES2CES1LMNA | |
| Ethylene Glycol SCHEMBL28101539 | 0.81 | CES2 (0.50) | SMN1; SMN2CES2CES1LMNAPLG | |
| Cyclohexane SCHEMBL28236664 | 0.81 | CES2 (0.55) | SMN1; SMN2CES2CES1LMNAPLG | |
| SCHEMBL25212375 | 0.81 | CES2 (0.61) | SMN1; SMN2CES2CES1LMNAPLG | |
| SCHEMBL242069 | 0.81 | CES2 (0.61) | SMN1; SMN2CES2CES1LMNAPLG | |
| SCHEMBL5493736 | 0.81 | CES2 (0.61) | SMN1; SMN2CES2CES1LMNAPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288335-A | REACTING ESTER WITH PHOSPHORUS SULFIDE, METAL OXIDE | OROGIL (FR) | 1981-09-08 | — | — | US | disclosed |