SCHEMBL2847820

SCHEMBL2847820

CC(C)(CO)CO.O=C(O)C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
HSD17B10 Q99714 1/20 0.46
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
LMNA P02545 3/20 0.38
PLG P00747 1/20 0.38
PLAT P00750 1/20 0.38
BTK Q06187 1/20 0.38
TSHR P16473 4/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37
GABRB2 P47870 1/20 0.37
GABRA4 P48169 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11401804 0.89 SMN1; SMN2 (0.42) SMN1; SMN2HSD17B10CES2CES1LMNA
SCHEMBL9436669 0.83 CES2 (0.44) SMN1; SMN2HSD17B10CES2CES1LMNA
Formic Acid SCHEMBL2161063 0.81 SMN1; SMN2 (0.37) SMN1; SMN2HSD17B10CES2CES1LMNA
SCHEMBL11496713 0.81 PEPD (0.44) SMN1; SMN2LMNAALDH1A1
SCHEMBL10770969 0.81 PEPD (0.44) SMN1; SMN2LMNAALDH1A1
Alcohol SCHEMBL27732747 0.80 CES2 (0.46) SMN1; SMN2CES2CES1LMNAPLG
SCHEMBL18140096 0.80 CES2 (0.38) SMN1; SMN2HSD17B10CES2CES1LMNA
SCHEMBL813277 0.80 CES2 (0.38) SMN1; SMN2HSD17B10CES2CES1LMNA
Ethylene Glycol SCHEMBL28101539 0.80 CES2 (0.50) SMN1; SMN2CES2CES1LMNAPLG
Cyclohexane SCHEMBL28236664 0.79 CES2 (0.55) SMN1; SMN2CES2CES1LMNAPLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100130390-A1 Multifunctional Driveline Fluid THE LUBRIZOL CORPORATION (US) 2010-05-27 US disclosed
EP-2121881-A2 MULTIFUNCTIONAL DRIVELINE FLUID The Lubrizol Corporation (US) 2009-11-25 EP disclosed
WO-2008112724-A2 MULTIFUNCTIONAL DRIVELINE FLUID THE LUBRIZOL CORPORATION (US) 2008-09-18 WO disclosed
EP-0319580-B1 TRACTION FLUID TONEN CORP (JP) 1993-12-22 EP disclosed
EP-0344307-B1 TRACTION FLUID Tonen Corporation (JP) 1993-08-11 EP disclosed
US-5085792-A Cyclohexanol-esterified dicarboxylic acid and a brached poly-alpha-olefin; transmission fluids TOA NENRYO KOGYO, K.K. (JP) 1992-02-04 US disclosed
US-4886614-A DIESTER OF CYCLOHEXANE TOA NENRYO KOGYO, K.K. (JP) 1989-12-12 US disclosed
EP-0344307-A1 TRACTION FLUID Tonen Corporation (JP) 1989-12-06 EP disclosed
EP-0319580-A1 TRACTION FLUID Tonen Corporation (JP) 1989-06-14 EP disclosed