Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017865 | 0.87 | KDM4E (0.54) | MEN1KMT2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL21881560 | 0.86 | MEN1 (0.58) | MEN1KMT2APPARAKDM4EALDH1A1 | |
| SCHEMBL5944601 | 0.86 | MEN1 (0.58) | MEN1KMT2APPARAKDM4EALDH1A1 | |
| SCHEMBL14303460 | 0.85 | PPARG (0.54) | MEN1KMT2APPARAKDM4EALDH1A1 | |
| SCHEMBL8114221 | 0.84 | MEN1 (0.45) | MEN1KMT2AMTNR1AMTNR1BLMNA | |
| SCHEMBL4529400 | 0.84 | TSHR (0.50) | MEN1KMT2AMTNR1AMTNR1BLMNA | |
| SCHEMBL21881586 | 0.84 | KDM4E (0.55) | MEN1KMT2APPARAKDM4EALDH1A1 | |
| SCHEMBL660871 | 0.84 | KDM4E (0.55) | MEN1KMT2APPARAKDM4EALDH1A1 | |
| SCHEMBL13324879 | 0.84 | KDM4E (0.55) | MEN1KMT2APPARAKDM4EALDH1A1 | |
| SCHEMBL10514685 | 0.83 | PGR (0.51) | KMT2AMTNR1AMTNR1BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271160-A | Substituted morpholine derivatives and pharmaceutical compositions | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-06-02 | — | — | US | disclosed |
| US-4229449-A | ANTIDEPRESSANTS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1980-10-21 | — | — | US | disclosed |