Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23490184 | 0.98 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL20621280 | 0.98 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL19779350 | 0.98 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL19779490 | 0.98 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL21776125 | 0.93 | GNAI3 (0.45) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22778647 | 0.89 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22962004 | 0.89 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22962251 | 0.89 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22962072 | 0.89 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22962144 | 0.89 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |