Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435940 | 0.75 | GBA1 (0.47) | KDM4EGBA1ALDH1A1L3MBTL1 | |
| SCHEMBL10458192 | 0.72 | L3MBTL1 (0.38) | KDM4EGBA1L3MBTL1 | |
| SCHEMBL11371658 | 0.70 | GAA (0.40) | TSHRGBA1L3MBTL1 | |
| SCHEMBL8434874 | 0.69 | L3MBTL1 (0.56) | GBA1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11367947 | 0.68 | GBA1 (0.41) | TSHRKDM4EGBA1ALDH1A1L3MBTL1 | |
| SCHEMBL9972944 | 0.68 | L3MBTL1 (0.50) | KDM4EGBA1L3MBTL1 | |
| SCHEMBL11359259 | 0.68 | GBA1 (0.70) | TSHRKDM4EGBA1ALDH1A1MAPT | |
| SCHEMBL11317793 | 0.67 | GBA1 (0.53) | GBA1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11328124 | 0.67 | L3MBTL1 (0.34) | KDM4EGBA1L3MBTL1 | |
| SCHEMBL8431952 | 0.67 | L3MBTL1 (0.39) | KDM4EGBA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4300973-A | ADDING AN IMIDAZOLIDINONE | AMERICAN CYANAMID COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4284536-A | IMIDAZOLIDINONE ADDITIVE | AMERICAN CYANAMID CO. (US) | 1981-08-18 | — | — | US | disclosed |