Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404211 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL11408177 | 0.87 | KDM4E (0.53) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL11408174 | 0.87 | KDM4E (0.53) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL11404090 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL11404092 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| N-Benzylideneanthranilic Acid SCHEMBL11423123 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| N-Benzylideneanthranilic Acid SCHEMBL11423120 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| N-Benzylideneanthranilic Acid SCHEMBL19924599 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL11408187 | 0.79 | PTGS2 (0.50) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL11408184 | 0.79 | PTGS2 (0.50) | ALDH1A1KDM4EHPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187317-A | Sunscreen and erythema treating with N-benzylidene anilenes | WILLIAM H. RORER, INC. (US) | 1980-02-05 | — | — | US | disclosed |