Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | G6PD | P11413 | 3/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414227 | 0.90 | ALDH1A1 (0.81) | ALDH1A1MAPTNPC1G6PDHSP90AA1 | |
| SCHEMBL11410425 | 0.81 | MAPT (0.69) | ALDH1A1MAPTNPC1G6PDHSP90AA1 | |
| SCHEMBL13186603 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTNPC1G6PDHSP90AA1 | |
| SCHEMBL11414134 | 0.81 | MAPT (0.69) | ALDH1A1MAPTNPC1G6PDHSP90AA1 | |
| SCHEMBL11412993 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTNPC1G6PDHSP90AA1 | |
| SCHEMBL11410228 | 0.81 | MAPT (0.69) | ALDH1A1MAPTNPC1G6PDHSP90AA1 | |
| SCHEMBL11407123 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTNPC1G6PDHSP90AA1 | |
| SCHEMBL11403099 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTNPC1G6PDHSP90AA1 | |
| SCHEMBL8041871 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTNPC1G6PDALOX15 | |
| SCHEMBL11420970 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTNPC1G6PDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |