Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404531 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2AMEN1APP | |
| SCHEMBL12018202 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2AMEN1APP | |
| SCHEMBL900894 | 0.82 | ALDH1A1 (0.75) | ALDH1A1MAPTKMT2AMEN1APP | |
| SCHEMBL900893 | 0.82 | ALDH1A1 (0.75) | ALDH1A1MAPTKMT2AMEN1APP | |
| 4-Nitroaniline SCHEMBL16451 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2AMEN1ESR1 | |
| 4-Nitroaniline SCHEMBL27963818 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2AMEN1ESR1 | |
| SCHEMBL9065915 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2AMEN1ESR1 | |
| 4-Nitroaniline SCHEMBL13529022 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2AMEN1ESR1 | |
| SCHEMBL11410425 | 0.81 | MAPT (0.69) | ALDH1A1MAPTAPPFBP1NPC1 | |
| SCHEMBL11404347 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2AMEN1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894286-A1 | NITRONE COMPOUNDS AS PHOTOPOLYMER POLYMERIZATION INHIBITORS AND CONTRAST ENHANCING ADDITIVES | AlliedSignal Inc. (US) | 1999-02-03 | — | — | EP | claimed |
| WO-1997040421-A1 | NITRONE COMPOUNDS AS PHOTOPOLYMER POLYMERIZATION INHIBITORS AND CONTRAST ENHANCING ADDITIVES | ALLIEDSIGNAL INC. (US) | 1997-10-30 | — | — | WO | claimed |
| US-6162579-A | Nitrone compounds as photopolymer polymerization inhibitors and contrast enhancing additives | CORNING INCORPORATED (US) | 2000-12-19 | — | — | US | disclosed |
| EP-0894286-A1 | NITRONE COMPOUNDS AS PHOTOPOLYMER POLYMERIZATION INHIBITORS AND CONTRAST ENHANCING ADDITIVES | AlliedSignal Inc. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997040421-A1 | NITRONE COMPOUNDS AS PHOTOPOLYMER POLYMERIZATION INHIBITORS AND CONTRAST ENHANCING ADDITIVES | ALLIEDSIGNAL INC. (US) | 1997-10-30 | — | — | WO | disclosed |