Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404359 | 1.00 | ITGB3 (0.52) | ITGB3ITGA2BMMP2MMP9HDAC1 | |
| SCHEMBL11397298 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BMMP2MMP9HDAC1 | |
| SCHEMBL11397295 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BMMP2MMP9HDAC1 | |
| SCHEMBL7286797 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BACE | |
| SCHEMBL9041411 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BACE | |
| SCHEMBL9041150 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BACE | |
| Methanesulfonamide SCHEMBL11103046 | 0.79 | ITGB3 (0.56) | ITGB3ITGA2BACE | |
| SCHEMBL10666091 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BHDAC1HDAC8TSHR | |
| SCHEMBL13811751 | 0.78 | HDAC8 (0.51) | ITGB3ITGA2BHDAC1HDAC8CTSS | |
| SCHEMBL7288661 | 0.77 | ITGB3 (0.58) | ITGB3ITGA2BMMP2MMP9HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036713-A2 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-30 | — | — | EP | disclosed |