Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313646 | 1.00 | ITGB3 (0.58) | ITGB3ITGA2BF2PRSS1ACE | |
| SCHEMBL7286797 | 0.92 | ITGB3 (0.60) | ITGB3ITGA2BACE | |
| SCHEMBL9041411 | 0.92 | ITGB3 (0.60) | ITGB3ITGA2BACE | |
| SCHEMBL7323333 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BACE | |
| SCHEMBL9041150 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BF2PRSS1ACE | |
| Methanesulfonamide SCHEMBL11103046 | 0.87 | ITGB3 (0.56) | ITGB3ITGA2BACE | |
| SCHEMBL8254962 | 0.84 | CTSK (0.50) | ITGB3ITGA2BF2PRSS1ACE | |
| SCHEMBL7310228 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BACEKLK5PEPD | |
| SCHEMBL4905274 | 0.83 | DPP4 (0.59) | ITGB3ITGA2BDPP4DPP8 | |
| SCHEMBL8661714 | 0.83 | DPP7 (0.56) | DPP4DPP8PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266568-A2 | Novel gamma-butyrolactone derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |
| EP-0084941-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-11 | — | — | EP | disclosed |
| EP-0084941-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-03 | — | — | EP | disclosed |